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Stress Response

One aim of the Stress Response program is to discover the factors that predict differences in stress reactivity among individuals and subsequently explore the biological mechanisms of stress vulnerability and stress resilience for prevention and effective treatment of stress-related disorders.

A second aim of the Stress Response program is to explore how a shift in photoperiods and more complex circadian disruptions may affect an individual’s response to stressors. Technologies to control regulation of the hypothalamic-pituitary-adrenal (stress) axis are desired for optimal physiological function and survivability of an individual.

Research Concentration Areas

  • Individual differences in response to stress
  • Effect of photoperiod changes (model of circadian disruption) on stress axis reactivity

Research Challenges and Opportunities

  • Biomarkers of stress resilience versus stress vulnerability in humans
  • Mechanisms of resilience versus susceptibility to stress
  • Delineate interactions between photoperiods, circadian rhythm alterations and stress reactivity

How to Submit

For detailed application and submission information for this research topic, please refer to our broad agency announcement (BAA) No. N00014-22-S-B001.

Contracts: All white papers and full proposals for contracts must be submitted through FedConnect; instructions are included in the BAA.

Grants: All white papers for grants must be submitted through FedConnect, and full proposals for grants must be submitted through; instructions are included in the BAA.


Morgan, Richard G. Lt.
Program Officer
Code 342